1. However it does create abnormal second polar bodies and therefore possible aneuploid zygotes. 2. ANI-1 is also crucial for segregation of polar bodies during meiosis. 3. Polar bodies are nonfunctional and incapable of being fertilized.4. In theory, molecular analysis of polar bodies may include epigenetic profiling in the near future. 5. The pictured oocyte has an extruded polar body at about 12 o'clock indicating its maturity. 6. However, chromosomally abnormal polar bodies are not guaranteed to induce the development of an abnormal zygote. 7. The oocyte now undergoes its second meiotic division producing the haploid ovum and releasing a polar body . 8. The oocysts have a polar body and a prominent residuum but lack micropyles, sporocyst residua or Stieda bodies. 9. Potentially, polar body biopsy may be used for molecular analysis, and can be used for preimplantation genetic screening. 10. Therefore, the formation of the first polar body is an especially important factor in forming a healthy zygote.